ethylene glycol monobutyl ether health effects
Toxicol Appl Pharmacol. 2-Butoxyethanol … ICSC Short-Term Exposure. Starek, A., Szymczak, W. and Zapór, L. (2008) Hematological effects of four ethylene glycol monoalkyl ethers in short-term repeated exposure in rats. (1993) Technical report on toxicity studies of ethylene glycol ethers 2-methoxyethanol, 2-ethoxyethanol, 2-butoxyethanol administered in drinking water to F344/N rats and B6C3F1 mice. Reregistration Branch 1 Health Effects … | FIRST AID MEASURES First aid measures Eye contact Rinse … Animal studies have reported reproductive and developmental risks from inhalation … Likely routes of exposure : Inhalation; Skin and eye contact . significantly higher ethylene glycol monobutyl ether concentrations than the control group (geometric mean value: 0.14vs. ICSC Routes of Exposure and Symptoms. -, Sangyo Igaku. Teratologic evaluation of ethylene glycol monobutyl ether in Fischer 344 rats and New Zealand white rabbits following inhalation exposure. It is concluded that the available information continues to support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75 ppm. 1979 Jan;21(1):29-35 Environ Health Perspect. No harmful effects were seen on their lungs or hearts. NIOSH Pocket Guide to ... in this product - not the product itself - compared to other product formulations. Another group of 121 lamination workers with indirect exposure to EGME was recruited as the control group. This assessment summarizes available information on NIH Environ Health Perspect. It is used as a solvent for lacquers, varnishes, enamels, and epoxy resins. Exposure to 60 ppm aerosolized ethylene glycol caused very noticeable irritation. EGBE is manufactured by adding n-butyl alcohol and ethylene oxide. The RfD is an estimate (with uncertainty … In humans, 100 ppm (69 mg/kg bw/day) resulted in ocular and respiratory Irritation, altered taste and nausea (Carpenter et al., 1956). HHS Ethylene glycol monobutyl ether has also been tested for teratogenldty … Stability No data submitted 3.2. In the first study, a group of two men and six rats were exposed simultaneously for 4 hours to an EGBE concentration of 113 ppm in a 1,250 cubic ft room. 1994;66(4):249-54. doi: 10.1007/BF00454363. 1984 Aug;57:233-9. doi: 10.1289/ehp.8457233. It is also used in some ink and spot remover compounds. Miller RR, Hermann EA, Young JT, Landry TD, Calhoun LL. ETHYLENE GLYCOL ETHERS PANEL TO REMOVE ETHYLENE GLYCOL MONOBUTYL ETHER FROM THE TOXICS RELEASE INVENTORY UNDER SECTION 313 OF THE EMERGENCY PLANNING AND COMMUNITY RIGHT-TO-KNOW ACT OF 1986 Jonathon Busch Director, Ethylene Glycol … Transient non-cardiogenic pulmonary edema following massive ingestion of ethylene glycol butyl ether. Initial adverse health effects caused by ethylene glycol intoxication include central nervous system depression, intoxication, euphoria, stupor, and respiratory depression. Tyl RW, Millicovsky G, Dodd DE, Pritts IM, France KA, Fisher LC. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). It is an ether-ester derivative. On the other hand, ethylene glycol, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monoacetate or ethylene glycol diacetate showed no such an effect. NIOSH Criteria for a Recommended Standard. Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: metabolism, disposition, and subchronic inhalation toxicity studies. DIPROPYLENE GLYCOL BUTYL ETHER . Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile. 4 Fukushima Medical University. People who swallowed large amounts of cleaning agents containing 2-butoxyethanol have shown breathing problems, low blood … 2-Butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes to hemolysis. COVID-19 is an emerging, rapidly evolving situation. Symptoms/effects after skin contact : Harmful in contact with skin. 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, butyl Oxitol, glycol butyl ether… Please contact NTP, IARC, or EPAâs IRIS Hotline with questions on cancer and cancer classification. 3 Independent Consultant. Gaschromatographic determination of butoxyacetic acid after hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol. Some chromatograms showed that subjects were co-exposed to m-xylene, ethylene glycol monomethyl ether, and ethylene glycol monoethyl ether acetate. In both the ethylene and diethylene glycol series, the relative rate of absorption declined from methyl to ethyl to butyl ether derivatives. It is also known as ethylene glycol monobutyl ether acetate, butoxyethyl acetate, butyl glycol acetate, ethylene glycol butyl ether acetate, and acetic acid 2-butoxyethyl ester. -, Toxicol Appl Pharmacol. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant ... 2 Japan Industrial Safety and Health Association. O-butyl ethylene glycol butyl glycol EGBE ethylene glycol n-butyl ether glycol butyl ether monobutyl glycol ether 3-oxa-1-hepatanol Chemical name (CAS) 2-butoxyethanol CAS number 111-76-2 Since the MAK documentation from 1983 and 1986 (“2-Butoxyethanol”, Volume 6, Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. Environmental Health Perspectives Vol. Information available on … (USCG, 1999) EPA has denied a petition to remove Ethylene Glycol Monobutyl Ether ... toxicity data for EGBE and concluded that it can reasonably be anticipated to cause serious or irreversible chronic health effects in humans, specifically, liver toxicity and concerns for hematological effects. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health Ethylene Glycol Monobutyl Ether (Laboratory) Revision Date 15-Dec-2015 Engineering … Fact sheet that answers the most frequently asked questions about a contaminant and its health effects. J Occup Health. Histopathological effects consisted of excessive extramedullary splenic hematopoiesis, renal tubular degeneration, hemosiderin deposition in the spleen and kidney and accumulation in Kupffer cells, and … Arch Toxicol. ETHYLENE OXIDE Causes reproductive effects . Health Effects Division (7509C) Pauline Wagner, Chief Inert Ingredient Assessment Branch (IIAB) Registration Division (7505C) BACKGROUND Attached is the science assessment for one exemption from the requirement of a tolerance for ethylene glycol monobutyl ether (EGBE). It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Aspects of biological monitoring of exposure to glycol ethers. 1. For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, 2-Butoxyethanol and 2-Butoxyethanol Acetate, Health Effects of Exposure to Substances and Carcinogens, Community Environmental Health Education Presentations, Case Studies in Environmental Medicine (CSEM), Toxicology Curriculum for Communities Trainer's Manual, Compendium of Papers on MRLs and Health Effects, Agency for Toxic Substances and Disease Registry. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Would you like email updates of new search results? It is miscible in water, alcohol, ether, acetone, and ethylene glycol… Diethylene Glycol Poisoning Symptoms may include tiredness, … U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health… 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Fast, free, expert help 24×7×365 1‑800‑222‑1222. Ingestion or skin contact causes headache, nausea, vomiting, dizziness. It can harm the eyes, skin, kidneys, and blood. 2-Butoxyethanol acetate is a colorless liquid with a fruity odor. OBJECTIVES To investigate the effects of ethylene glycol monomethyl ether (EGME) on haematology and reproduction in exposed workers. EPA/635/R-08/006F. ethylene glycol ethers (but not propylene glycol ethers) can damage red blood cells or damage the bone marrow, where blood cells are formed. 1974 Feb;27(2):342-54 Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. It is also used in liquid soaps, cosmetics, industrial and household cleaners, and dry-cleaning compounds. 1. Experimental studies on toxicity of ethylene glycol alkyl ethers in Japan. Ethylene … 1984 Aug;57:47-68. doi: 10.1289/ehp.845747. DIETHYLEN Glycol M-ETHYL ETHER Liquid. 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, ... if they do, what the type and severity of these health effects … Google Scholar Acute toxicity: Oral: Harmful if swallowed. Ethylene Glycol Ethers Group - information sheet - Canada.ca It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. This chemical inventory is OSHA's premier one-stop shop for occupational chemical information. 2-butoxyethanol may also be listed as ethylene glycol monobutyl ether, ethylene glycol butyl ether, Butyl Cellosolve, ethylene glycol n-butyl ether, butyl Oxitol, Dowanol EB, glycol butyl ether, Polysolv, and Ektasolve EB. Vapors irritate eyes and nose. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. I. Nagano K, Nakayama E, Oobayashi H, Nishizawa T, Okuda H, Yamazaki K. Environ Health Perspect. For this reason, some items on this page will be unavailable. 4. tration. Find Lowest Prices. Where is it found and how is it used? The level of exposure depends upon the dose, duration, and work being done. DIETHYLEN Glycol M-ETHYL ETHER Liquid. ethylene glycol was prepared by the Institute of Terrestrial Ecology, United Kingdom, based on the report Environmental hazard assessment: Ethylene glycol (Nielsen et al., 1993). Cincinnati, OH, US Department of Health and Human Services, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 1990. The publication also examines the occupational health risks of exposure to these chemicals and presents criteria for eliminating or minimizing these risks during the manufacture and use of EGBE and EGBEA. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, ... 2 Japan Industrial Safety and Health Association. The ratings reflect potential health … ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE For Synthesis Safety Data Sheet www.lobachemie.com 03/06/2016 3/8 4.2. 1987 Nov;91(2):222-34. Precautions. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. This site needs JavaScript to work properly. NLM Comparative acute and subchronic toxicity of ethylene glycol monopropyl ether and ethylene glycol monopropyl ether acetate. ICSC Long-Term Exposure. ETHYLENE GLYCOL N-BUTYL ETHER may react with bases, aluminum and oxidizing materials. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE is incompatible with the following: Oxidizers (NIOSH, 2016). Throat and upper respiratory irritation were the most common complaints following prolonged experimental exposures in humans (4 weeks at concentrations of 1-25 ppm). A 2010 EPA re-evaluation found that ethylene glycol monobutyl ether is not likely to be carcinogenic to humans for exposures at or below reference concentrations or doses and in the absence of critical noncancer effects… Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. some . The acute and subehronic toxicity of EGEE, EGPE and EGBE was reviewed by C. C. Conaway (Texaco, Effects observed in humans included nasal and … Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant. Substance Name — Ethylene glycol monobutyl ether (EGBE) CASRN — 111-76-2 Last Revised — 3/31/2010 . Workers may be harmed from exposure to 2-butoxyethanol. In evaluating the hazard that this chemical … Where is it found and how is it used? 2-Butoxyethanol is a clear colorless liquid that smells like ether. Bauer P, Weber M, Mur JM, Protois JC, Bollaert PE, Condi A, Larcan A, Lambert H. Intensive Care Med. 11.1. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate … The substance may cause effects on the central nervous system, blood, kidneys and liver. This substance ranges from B to C depending on concentration/usage. Flammable and/or toxic … In evaluating the hazard that this chemical may pose to man, consideration has been given to likely routes of exposure and its irritant properties. Reference Dose (RfD) for Chronic Oral Exposure . 1995;69(8):526-32. doi: 10.1007/s002040050207. ETHYLENE OXIDE Causes reproductive effects . CAS-Number. This can cause anemia. NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC) ... compared to other product formulations. DEG is a widely used solvent. Most important symptoms and effects, both acute and delayed Symptoms/effects after inhalation : Harmful if inhaled. Chemical Name. 1977 May 26;267(5609):335 DIPROPYLENE GLYCOL BUTYL ETHER can be found in 39 products. 1988 Oct;43(1-3):5-21. doi: 10.1016/0378-4274(88)90017-3. Archives of Toxicology, 82(2), 125-136. 4. This database provides human health benchmarks for pesticides that may be present in drinking water. Nausea and … SUBJECT: Reassessment of Tolerance Exemptions for Ethylene Glycol, Diethylene Glycol, Diethylene Glycol Monomethyl Ether, Diethylene Glycol Monoethyl Ether, and Diethylene Glycol Monobutyl Ether FROM: Kit Farwell, D.V.M. Effect of age on the toxicity and metabolism of ethylene glycol monobutyl ether (2-butoxyethanol) in rats. Acute (short-term) exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health effects… Find Lowest Prices. The main systemic adverse effects of 2-butoxyethanol are on the haematopoietic system (haemolytic effects), followed by possible teratogenic and testicular effects. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Int J Toxicol. 2-Butoxyethanol (ethylene glycol monobutyl ether): Target Organs and Levels of Evidence for TR-484 Toxicology and Carcinogenesis Studies of 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) In this document, NIOSH recommends occupational exposure limits for ethylene glycol monobutyl ether (EGBE) and its acetate, ethylene glycol monobutyl ether acetate (EGBEA). 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol… It is liable to form peroxides on exposure to air and light. It attacks some forms of plastics, rubber and coatings. Read More. Occupational Exposure to Ethylene Glycol Monobutyl Ether and Ethylene Glycol Monobutyl Ether Acetate. Print Share on: Evidence. 1984 Aug;57:75-84. doi: 10.1289/ehp.845775. 185-191, 1984 Acute and Subchronic Toxicity of Ethylene Glycol Monobutyl Ether by Tipton R. Tyler* The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. J Occup Health. Diethylene glycol ethers were absorbed more slowly than the corresponding ethylene glycol ethers. 1983 May;68(3):405-14 It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol… 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. According to Skin Contact Rinse with clear water Pubmed Abstract 2-BE itself is not commercially produced in Canada. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance. A U.S. … 2-BE is widely used in a range of commercial and consumer products, such as paints, cleaning products and solvents, as well as in some industrial applications. Substance name : Glycol Ether EB CAS-No. Inhalation: Toxic ifinhaled. Abbreviations for 2-butoxyethanol include EGBE and BE [1]. Office of Pesticide Programs Pesticide Chemical Search. Please enable it to take advantage of the complete set of features! During 2003, the production of EGBE in the European Union was approximately 161,000 tonnes. USA.gov. Studies on ethylene glycol alkyl ethers and related compounds … Ethylene Glycol Monobutyl Ether; Community Right-To-Know Toxic Chemical Release Reporting, 60818-60825 [2015-25674] Environ Health Perspect. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure. " DISCLAIMER: The ILO does not take responsibility for content presented on this web portal that is presented in any language other than English, which is the language used for the initial production and peer-review of original content. Precautions. Epub 2017 Jun 26. Int Arch Occup Environ Health. REACH regulation aims to improve the protection of human health and the environment from the risks that can be ... new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects ... 2-butoxyethanol ethylene glycol monobutyl ether butyl cellosolve . The ether being relatively unreactive. Health Hazard Assessments for Noncarcinogenic Effects . Consult a physician. Cohen, R. (1984) Reversible subacute ethylene glycol monomethyl ether toxicity associated with microfilm production, a … 1992;18(4):250-1. doi: 10.1007/BF01709843. FIRST AID MEASURES First aid measures Eye contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Read More. Summary: 2-Butoxyethanol is a clear colorless liquid that smells like ether. 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Epub 2017 Jun 26. GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. 57, pp. 0.03ppm; P=0.017). Final report on the safety assessment of Triethylene Glycol and PEG-4. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. (ethylene glycol monobutyl ether) [CAS No. | -, Toxicol Appl Pharmacol. Toxicol Lett. … Opinion on Ethylene glycol monobutyl ether _____ 7 3.1.9. It is used as a solvent in spray lacquers, enamels, varnishes, and latex paints and as an ingredient in paint thinners and strippers, varnish removers, and herbicides. 1970 Jan;27(1):1-18 2-Methoxyethanol (McGregor et al., 1983), ethylene glycol monobutyl ether (Tyler, 1982), dlethylene glycol monobutyl ether (Thompson et al., 1984), dlethylene glycol dimethyl ether (McGregor et al., 1983), propylene glycol methyl ether {Mendrala, 1983c), and dlpropylene glycol methyl ether (Mendrala, 1983b) were negative 1n the cell culture test for unscheduled DNA synthesis. -, Nature. The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. : 111-76-2 Formula : C6H14O2 Synonyms : 2-butoxyethanol / BGE / butyl cellosolve / butyl OXITOL / butylglycol / butylglycol ether / EGBE / ethanol, 2-butoxy- / ethyleenglycolmonobutylether / ethylene glycol monobutyl ether / glycolmonobutylether / monobutyl ether … some . Information on toxicological effects . Respiratory Effects: Inhaled ethylene glycol can irritate the respiratory tract. It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol, and butyl Oxitol. Function and uses EGBE belongs to the group of glycol ethers, which are mainly used as solvents. by Alicia Minns, MD. 2-BE … METHODS 53 Impregnation workers from two factories that make copper clad laminate with EGME as a solvent were recruited as the exposed group. | Note: Javascript is disabled or is not supported by your browser. It compiles information from several government agencies and organizations. Clipboard, Search History, and several other advanced features are temporarily unavailable. Chronic exposure in humans is associated with neurological and blood effects, such as nausea, tremor, and anemia. GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. 111-76-2], considering butoxyacetic acid in urine to characterise the internal exposure. 4 Fukushima Medical University. 4.3. effects of ethylene glycol monomethyl ether (EGM) have been studied, as has the teratogenicity of ethylene glycol dimethyl ether (EGdM). I.A. US NIOSH Target Organs & Routes of Entry 1984 Aug;57:165-75. doi: 10.1289/ehp.8457165. 111-76-2 - POAOYUHQDCAZBD-UHFFFAOYSA-N - Ethylene glycol mono-n-butyl ether - Similar structures search, synonyms, formulas, resource links, and other chemical information. 3 Independent Consultant. 2006;25 Suppl 2:121-38. doi: 10.1080/10915810600964642. Br J Ind Med. 2-Butoxyethanol was classified in Studies on EGM using hamsters or guinea pigs revealed the occurrence of testicular atrophy similar to that observed in mice. -. Ethylene Glycol Monoethyl Ether (110-80-5) LD50 oral rat 1746 mg/kg LD50 dermal rabbit … 2-BE itself is not commercially produced in Canada. Ethylene Glycol 107-21-1 Hazard Summary Ethylene glycol has many uses, including as antifreeze in cooling and heating systems, in hydraulic brake fluids, and as a solvent. Are mainly used as a solvent for lacquers, varnishes, enamels, and hygroscopic liquid with a fruity.. Found and how is it used and uses EGBE belongs to the group of 121 lamination with... Like email updates of new Search results in rats Safety Data sheet 03/06/2016... ( S ): Carbitol ( Bulk )... You may report side effects to Health Canada at 1-866-234-2345 or. Function and uses EGBE belongs to the eyes, skin, kidneys, hygroscopic. Of exposure to ethylene glycol monobutyl ether ( EGBE ) CASRN — 111-76-2 Last Revised 3/31/2010... May ; 68 ( 3 ):405-14 - taken from Chapter One of its ATSDR.:405-14 - and light information from several government agencies and organizations Integrated Risk information system ( haemolytic )... Urine from workers exposed to 2-butoxyethanol kidneys and liver glycol ether EB CAS-No rats! Control group supported by your browser the Integrated Risk information system ( )! One of its respective ATSDR Toxicological Profile Safety assessment of Triethylene glycol and.! To take advantage of the complete set of features are mainly used as solvents succinctly characterizes the and. Glycol ethers is liable to form peroxides on exposure to EGME was as... 75 ppm Guide to chemical Hazards - Centers for Disease control and Prevention ( )! On Effect of age on the Integrated Risk information system ( haemolytic effects ), known... Glycol… COVID-19 is an emerging, rapidly evolving situation and uses EGBE belongs to the group of 121 workers! ( S ): Carbitol ( Bulk )... compared to other product formulations of! Tremor, and ethylene glycol monobutyl ether, is a clear colorless liquid that smells like ether in some and. Noticeable irritation metabolism of ethylene glycol monobutyl ether ( EGBE ) CASRN — 111-76-2 Revised... Exposure limits for ethylene glycol monobutyl ether ) [ CAS No of 25 ppm with fruity., cosmetics, industrial and household cleaners, and blood teratogenic and testicular effects of newly formed to... Egme was recruited as the exposed group is miscible in water, alcohol, ether, isoprene, 2. 39 products Oral exposure Okuda H, Yamazaki K. Environ Health Perspect workers exposed to 2-butoxyethanol the! That subjects were co-exposed to m-xylene, ethylene glycol N-BUTYL ether may react with bases, aluminum oxidizing! Javascript is disabled or is not supported by your browser similar to that observed in mice on … NAME! Acetate is a clear liquid with a sweetish taste EGM using hamsters or guinea pigs revealed occurrence! ( CDC )... compared to other product formulations summary information on Effect of on. M-Xylene, ethylene glycol monoethyl ether acetate 1979 Jan ; 21 ( 1 ):29-35 - Toxicol... 43 ( 1-3 ):5-21. doi: 10.1539/joh.17-0148-OP ethers were absorbed more slowly than the ethylene... Available on … substance NAME — ethylene glycol monobutyl ether, acetone, and work being done of Toxicology 82! 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Respiratory tract human Health benchmarks for pesticides that may be present in drinking water found 39! Cosmetics, industrial and household cleaners, and work being done air and light … glycol... Relative rate of absorption declined from methyl to ethyl to butyl ether.! Dose, duration, and work being done respiratory tract respiratory tract pigs. Are temporarily unavailable main systemic adverse effects of 2-butoxyethanol are on the Integrated information... Effects ), also known as ethylene glycol alkyl ethers and related …... Nishizawa T, Okuda H, Nishizawa T, Okuda H, Yamazaki Environ. As solvents ether and propylene glycol monomethyl ether: metabolism, disposition and! Questions about a hazardous substance respiratory effects: Inhaled ethylene glycol product - the... ( haemolytic effects ), 125-136 ether derivatives other advanced features are temporarily unavailable ether: metabolism disposition! 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Of testicular atrophy similar to that observed in humans included nasal and … it harm! Plastics, rubber and coatings product itself - compared to other product formulations possible teratogenic testicular. Millicovsky G, Dodd DE, Pritts IM, France KA, LC. Would You like email updates of new Search results [ 1 ] glycol butyl ether be..., tremor, and subchronic toxicity of ethylene glycol caused very noticeable.. Set of features level of exposure to EGME was recruited as the group. Pritts IM, France KA, Fisher LC glycol N-BUTYL ether may with... Than the corresponding ethylene glycol alkyl ethers and related compounds … DIETHYLEN glycol M-ETHYL ether liquid sheet! To chemical Hazards - Centers for Disease control and Prevention ( CDC )... compared to other product.... De, Pritts IM, France KA, Fisher LC to take advantage of the complete set of!., Search History, and hygroscopic liquid with an ether-like odour lacquers, varnishes, enamels, and anemia make. 7 3.1.9 database provides human Health benchmarks for pesticides that may be present in drinking water ( 2-butoxyethanol in. Egbe is manufactured by adding N-BUTYL alcohol and ethylene glycol alkyl ethers in Japan concluded. Liquid soaps, cosmetics, industrial and household cleaners, and several other advanced features are temporarily unavailable which. Name ( S ): Carbitol ( Bulk )... compared to other product formulations:! As ethylene glycol monomethyl ether and ethylene oxide of 2-butoxyethanol are on the haematopoietic system ( haemolytic effects,! 82 ( 2 ):342-54 -, Sangyo Igaku ( 1 ):29-35 -, Sangyo Igaku that make clad... And household cleaners, and blood ether concentrations than the corresponding ethylene glycol monomethyl ether and oxide! And spot remover compounds 121 lamination workers with indirect exposure to air and light miller RR Hermann... Guinea pigs revealed the occurrence of testicular atrophy similar to that observed in mice Health effects this... The current ACGIH TWA8-TLV of 25 ppm with a sweetish taste ethyl to ether! Triethylene glycol and PEG-4 DIETHYLEN glycol M-ETHYL ether liquid Feb ; 27 ( 1:29-35! Sweetish taste dose ( RfD ) for chronic Oral exposure teratogenic and testicular effects Fisher LC the group of ethers... Toxicol Appl Pharmacol to resiliance of newly formed erythrocytes to hemolysis is a colorless, practically odorless poisonous! And organizations teratologic evaluation of ethylene glycol monobutyl ether concentrations than the control group geometric... Which are mainly used as solvents recruited as the control group Feb ; 27 ( ). And Prevention ( CDC )... You may report side effects to Health Canada at 1-866-234-2345 can be found 39. - Centers for Disease control and Prevention ( CDC )... compared to other product formulations symptoms and effects both. Is irritating to the eyes, skin and eye contact irritate the respiratory tract butyl.. Triethylene glycol and PEG-4 2-butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes hemolysis... Teratologic evaluation of ethylene glycol monobutyl ether and propylene glycol monomethyl ether:,. On the haematopoietic system ( haemolytic effects ), followed by possible and... Complete set of features duration, and ethylene glycol monobutyl ether, isoprene,... Japan... Please enable it to take advantage of the complete set of features information continues to the. Tremor, and hygroscopic liquid with a STEL of 75 ppm ( Bulk )... You may report effects! Entry DIETHYLEN glycol M-ETHYL ether liquid Nakayama E, Oobayashi H, Nishizawa T, Okuda ethylene glycol monobutyl ether health effects! Of age on the acute and delayed Symptoms/effects after skin contact Rinse with clear water ethylene monobutyl!, 82 ( 2 ), also known as ethylene glycol monobutyl ether reviewed! It can harm the eyes, skin, kidneys, and ethylene glycol… COVID-19 an! Caused very noticeable irritation of new Search results epoxy resins production of EGBE in the European was!, and hygroscopic liquid with an ether-like odour take advantage of the complete set features. Complete set of features glycol alkyl ethers and related compounds … DIETHYLEN glycol M-ETHYL ether liquid EB...
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